Dan Akroyd and Jane Curtin as Richard and Pat Nixon.
Akroyd/Nixon (looking at portrait of JFK): "And you-- John Fitzgerald Kennedy. Having sexual relations. In the White House. With women! You haven't seen any of that in the Nixon administration."
Curtin/Pat Nixon: "Oh, Richard's not prejudiced-- he hates all minorities equally."
The classic Ackroyd/Curtin "Point-Counterpoint" show.
The Phil Hartmann sketch with a dominating, super-quick-witted, multilingual Ronald Reagan in total control of a covert arms dealing scheme, and then rapidly shifting to a friendly & slow-speaking demeanor for a photo-op with the Girl Scout Cookie sales champion.
The first Bush-Gore debate:
"Excuse me, Jim. I'd like to interrupt and answer this question as though you had asked it to me."
"Strategery."
"I love deadlines. I love the whooshing noise they make as they go by."
-Douglas Adams